From Mutation and Repair to Therapeutics
نویسندگان
چکیده
As DNA research has developed, in this Special Issue of DNA, we aimed to explore recent advancements, with an emphasis on the damage-induced alteration cellular functions [...]
منابع مشابه
Endothelial regrowth after arterial injury: from vascular repair to therapeutics.
Interventional strategies for patients with coronary artery disease such as percutaneous transluminal coronary angioplasty or coronary stent implantation invariably result in a Ž marked degree of vascular injury deendothelialization, . mechanical damage to the medial and adventitial layers w x 1–3 . The loss of the endothelial monolayer is associated with a variety of deleterious consequences s...
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15 صفحه اولepidemiological study of oral and pharyngeal cancers in kermanshah province from march 1993 to march 2006
چکیده ندارد.
15 صفحه اولfrom historical facts to geo-political realities: relation between turkey and armenia ( 1915 – 2010)
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15 صفحه اولMutation choice to eliminate buried free cysteines in protein therapeutics.
Buried free-cysteine (Cys) residues can contribute to an irreversible unfolding pathway that promotes protein aggregation, increases immunogenic potential, and significantly reduces protein functional half-life. Consequently, mutation of buried free-Cys residues can result in significant improvement in the storage, reconstitution, and pharmacokinetic properties of protein-based therapeutics. Mu...
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ژورنال
عنوان ژورنال: DNA
سال: 2023
ISSN: ['0198-0238', '2331-4672']
DOI: https://doi.org/10.3390/dna3020007